computer memory and execution performance, which is the best option?

[nrrpires]

Friends
My layout (Route, session or Scenario) is now more than 350 "Section" and I predict that come close to 500.
I asked:
There are free and clear spaces that occupy a section or more.
In terms of computer memory and execution performance, which is the best option:
- The section does not exist;
- Create a section and it is empty.
Thanks