If I understand you right, you d/loaded a/some route(s) without the needed dependencies. If you did so, no wonder you are having trouble with it. You need to d/load ALL dependencies the route(s) need, that means if for example you have to d/load a locomotive among others, you also need to d/load its dependencies like bogies, coronas, engine sound and engine specs etc. if needed with it.
Usually when accessing a particular item on the Download page of the item, these dependencies are listed on it. The same goes for all other content items needed for your route(s).
Cheers
VinnyBarb