Reinstalled TRS22 which didn't cure the no sound issue - it wasn't a clean install so I was not surprised.
I uninstalled and did a clean reinstall, and TSR22 ran with sound - which was nice.
I say WAS nice because the next day - no sound again.
Odd situation but as TRS19 is running fine, and I'm more than happy with it, TRS22 is shelved for now.
Thanks for your help.