Hello, nugget
I just want to say that you are a very brave man for undergoing such ambitious project, and I'd also like to say my best wishes and prayers go to your health. I think I will say a few things here, however I will not repeat the technical points the above users have stated, as far as the technical questions go, you seem to have your answer

.
But I will say this,... Whatever decision you make, whatever you choose to do, as far as Trainz, and especially your real life is concerned, we will respect whatever you choose to do. If you really wish to take on such a large project, by yourself, for that long a day, that frequently, I and everyone else will respect your decision.
However, like other posters in this thread have stated, who are far more intelligent than I, working on such a project, that much, that large, may not be very beneficial to your daily life, your experience with Trainz, or more importantly, your actual health.
I will say that I and the other members of the community wish what's best for you, especially your physical health. I think I will ask, only that you do what you feel is best for you, but also, I respectfully ask (not demand) that you respect your health, and keep your real life and family your top priority, as that is much more important than Trainz, and it is not worth compromising for this project.
In any case, a route project that large, even if it could be completed, it is doubtful the majority of the users here would have the machine power necessary to run it.
Once again, we respect whatever decision you will make, and we will do our best to provide all the support we can for you. We will remain with you for the whole journey, all the way, no matter what.
God bless your soul, and I wish you many healthy years to come, and a long and happy life :wave:
P.S. If I made any grammar or spelling errors, or if I sound a bit off, I do apologize, I'm using my mobile device right now and the touchscreen keyboard can be difficult to use often.