A spinning circle or hourglass means that the program and or the operating system are busy. If your hard disk is very fragment, spinning rust only, this can cause both to take longer to load data. A full disk will cause this as the OS and program are attempting in vain to find a place for temporary files.
If you are killing TRS22 then there's a 99.99% possibility you are corrupting your database which will lead to more problems and then more problems. Eventually, you'll have to run an EDR and create more problems for yourself.
Run a DBR and check for faulty assets and clean those up accordingly after you view errors and warnings.