A model RR layout could be covered with a bedsheet, plastic drop cloth, vinyl tarp ... etc ...
A wet dry vac with a 4" soft brush attachment, and possibly a small 1/2 hole drilled in the vvaaccuumm cleaner hose would reduce high powered suction (an could be pluged with duct tape for high powered suction). A leaf blower on low speed could blow dust off (and all over creation) ... and 2-3 portable fans would blow the airborne dust out the winder' :hehe: or back door.
And yes ... all scenery should be spayed with a windex bottle filled with water (with a couple drops of added liquid dishsoap, for making water wetter and not bead up) ... then drizzle diluted elmers white glue overall, and re-spray lightly untill the glue soaks in. This process of re-wetting, re-gluing, re-wetting the glue, sometimes takes several applications spread out over a weeks time ... to achive a rigid ballast/sawdust shell that won't vvaaccuumm up into the wet dry vac.