Hallo Kris,
thanks for your personal message.
Well, building a city is always challenging. Just if you have a look onto the Municipal Transit Railway Route inside TS12 you will see the result of about one year of work. It was about building some areas and improving it later on by considering the experiences I made while working at other areas.
If you study that route or even a US city on Google maps, you will see that the density of buildings is as most at the downtown area. There you have the tallest buildings close together and multi lane roads runs between them. As more you get away from downtown the buildings gets smaller. Also you have some areas of small service companies between the residential houses and apartments.
Some of your roads running through large buildings does not have sidewalks, but it should. Roads without sidewalks are untypical inside towns - perhaps between small companies but never in front of office or residential buildings.
Also you need to create some road crossovers from one side of the RR to the other. Just go with a bridge over the tracks or with a tunnel below them. Don't use level crossings for main roads too often. There should be a road going from one side of the RR to the other in a distance of about 800 to 1000 Meters. That means one crossover at nearly each baseboard.
Don't put residential houses too close to the tracks - leave a distance of about 10 Meters. Built a fence between the houses and the tracks so the people cannot just walk into the tracks. Also you need to put some grass, bushes and sometimes a little tree around that fence to create a stripe of vegetation going parallel to the tracks.
You start looks good and I see you are working passionately at your route - everybody likes it if somebody follows his intentions and wants to get something done in a good quality - just like you.
I agree with Hert - and I would recommend that you should just take some time to study some town maps at Google maps or some good example city routes at trainz. This time and such a investigation will help you to create your route even better. Still your screens indicates a very good start.
Keep up your good work and have fun doing so
Your's TUME