The only thing that could have avoided the crash would be a law where a lowboy truck would have to pull over to the side of a road, and inspector or RR official would come out and oversee the lowboy trailer crossing the RR, and notify trains to stop until the truck cleared the crossing.
That might be a little extreme. Simply use common sense.
In the worst-case scenario where if I had a lowboy in tow, lacking a prescribed route and useful information about this hazard, I'd do the following:
1. Approach crossing at very low speed, flashers on and ensuring that no vehicles behind you preventing a reverse maneuver if necessary.
2. Proceed forward with head out and constantly visually confirming that the lowboy is clearing the gradient.
3. If in doubt, quickly get out and visually confirm (from surface level) that the lowboy can and will clear the gradient.
4. Proceed forward in 3rd or 4th gear. The idea is to move under low torque.
5. If there is the slightest sign of resistance, immediately back away from the crossing.
5b. If the crossing is activated, immediately back away from the crossing.
This, of course, is in the worst case scenario lacking various measures that could have prevented such an accident. No police escort, no pilot car, no prescribed route, no assistant driver to provide visual guidance.
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What the driver could've also done - since he would've obviously had the keys to the crane and assuming he had enough time if he was thinking on his feet - is to drive said crane off the trailer. A collision with a lighter, empty trailer might have been the difference between the locomotive flipping over or just derailing/sustaining mild damage. It might have even allowed him to drag the trailer clear of the crossing.
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