Middleton for laptops will run on just about anything with a GPU higher than 338 on https://www.videocardbenchmark.net/gpu_list.php but it is very specialised and uses a number techniques to be able to run on low end hardware.
Having said that you really want a score of 10,000 for a reasonable system and the Ryzen7 4800U has integrated graphics of Radeon RX Vega 8 which scores 1552.
