Tomurban: Before I upgraded to new computers, I ran TRS2004 on my old XP/SP3 machine. It was that machine we originally created the DHR. That route has upwards of 400 boards and encompasses around 3500 pieces of content. It runs for 54 miles and has sessions with HTML assets which load right at the beginning. It usually took around 2 minutes to load the route and another 2 to get a session going. Once it did, however, it never had a glitch or stutter except in one spot which was very dense with scenery.
I have a feeling that there might be some advantage to making sure you've stopped all the background processes you can and temporarily turned off your anti-virus. I did not turn off my firewall even though I'm behind a hardware firewall in my router. Perhaps fiddling with your OS settings like swap files and the like might give you some more RAM.
Bill