What's cool about T:ANE (or TS12, for that matter) is that an incredibly simple backup regime may be achieved by simply copying your entire T:ANE or TS12 installation folders over to another drive. (You don't have to worry about system registry issues).
If you do this regularly and copy properly-working versions to a safe backup hard drive location elsewhere, then if something bad happens to your primary installation rendering it inaccessible or too badly corrupted to work properly, you simply delete that installation and copy back (into the same location as the original) your backup version.
Yeah, sure, it takes up precious time and a lot of hard drive space to do this (but it can be initiated and left to occur in the background while you do other stuff) but most of us now have multi-terabyte drives that are underutilised otherwise.
Even laptop users can easily attach a USB 3.x external drive for this purpose.
The only 'gotchas!' that might trip this method up is to fail to also back up - and reinstate in the correct location(s) - files like the userdata-redirect-map.txt in your Appdata folder on your boot drive and assets.tdx etc. in your TANE folder that prevailed at the time of your 'snapshot of working version' copy.