It may well be the different sound systems between the two versions. I have TRS19 and I have an LG Full HD sound driver that came with an LG Monitor. Unfortunately, it often comes "unchecked" in the sound control panel, and then I have no sound until I go into the sound control panel and re-check it. I have been unable to figure out why this happens, but I do know that if it is "unchecked" when I start TRS19, I will have no sound at all, even if I do go in and re-check it in the sound control panel. The sound HAS to be working when I start Trainz because it will never check or connect to it once it is running. Other apps will, but not TrainzTRS19. I don't know if you have any kind of issue like this, but just be aware that if for any reason your sound was not connected or was disabled when you started Trainz, you will have to close it all the way out and bring it up again while the sound is active. I do not have 22 yet, so cannot say if that works differently.