Right, purchased TRS22 and played around with it for a bit. Few things I wanted to point out for anyone interested in buying it through Steam with the sale:
1: All of the content that I purchased through N3V was still available to use, and I was able to easily reset the data folder to the one I used for TRS19 so that I didn't have to reinstall anything, though the database rebuild did take quite a while. Honestly, you'll probably want to buy all of your DLC content through N3V's store (rather than Steam) so that you can access store points for future discounts, as well as having the ability to use your purchases in non-Steam copies of the game should you decide to buy a future version of the game from N3V directly.
2: I did a quick drive though part of my current CP&P route, and it performed well, at least even with TRS19, possibly better in some minor respects.
3: You will need a first-class ticket to download the new routes at any reasonable speed, as they do not come pre-installed - I don't have one currently, so I'll wait to download them until I do.
4: I have a decent internet connection, so it took less then 20 minutes for Steam to install the game on my laptop, though that's also in part because of my SSD. Still, reasonable installation time is a plus.