I am running the STEAM version of TS12 on my Win 11 computer with no issues. If you have actual media your results may vary according to service pack level.
I run the N3V version of TS12 on Windows 11 and it works fine. You need to run as administrator just as you do with Windows 7 and Windows 10. Other than that, it's same as always and seems to render a bit quicker too.