I couldn't find the information on TRS22, so I'm going out on the assumption that it's the same at least for now since it's still in beta because the graphics requirements only list the minimum hardware.
If your current system supports TRS19, it'll run TRS22 fine if not even better with smoother graphics and overall better performance going by my experience so far.
As mentioned many times in the Trainz Newsletter and on the Trainz Plus site, DX12 will be added to Trainz Plus and possibly to TRS22 in the coming year. Tony says it is pretty much complete.
It's been 3 years, where are you guys at with this? I just purchased Trainz 2022 and immediately noticed the horrendous stuttering that comes with DX11, I hope I can use the steam launch options can to override this like you can with Train Sim World, otherwise it will be a swift refund. This is really something I'd expect as part of the game though as it seems fairly new and the difference between DX11 and 12 is like night and day when it comes to performance.