There is a tutorial specifically called Realistic Controls. I have found that even after SP2 they don't always work very well though. The train brake, throttle and forwarder seem to want to move backwards from the mouse (Actually, I don't think I got the throttle to work at all), and I found if I tried to do in-cab on the Dynamic Brake tutorial, I could get started, but could not get any speed up, and eventually ground to a halt. There seems to be an issue with the brake pipe pressure with that one still, and holding the "D" key will not drain it. Also, in the Steam Tutorial, there are only one or two items that actually work.
“We are all travelers in the wilderness of this world, and the best we can find in our travels is an honest friend.” - R.L.S.