I myself have heard popping, but it's been from day 1. There's a route (can't recall the name) that has lots of cows, as each Mooo starts POP!
I don't care for the route so I didn't chase it down, but I also had it on a BNSF signal back when I switched to TANE - in that case the sound file had a large DC offset in the file. All I had to do was remove it (using Audacity) and it was fine again.
I don't know if the game, or the DLS, or something else corrupted it, or if it was always that way and for some reason it didn't make a pop in TS12, but AFAIK it was the exact same asset and in TS12 it was ok, and in T:ANE pop-pop-pop on each bell ring.
So, it's possible it's a similar issue.
I've also noticed in TRS19 that sounds cut off, and in cab they "surge" like channels are cutting out and overlapping.
I've felt for many versions that audio is a sorely neglected aspect of this game.
Sorry, I know none of this really helps you with your problem...